BDBM50206509 4-Dipropylsulfamoyl-benzoic acid::4-Dipropylsulfamoyl-benzoic acid anion::4-Dipropylsulfamoyl-benzoic acid(probenecid)::Benemid::CHEMBL897::PROBENECID::Probalan

SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O

InChI Key InChIKey=DBABZHXKTCFAPX-UHFFFAOYSA-N

Data  38 KI  27 IC50  1 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50206509   

TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataKi:  4.30E+3nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataKi:  4.41E+3nMAssay Description:TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataKi:  6.31E+3nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataKi:  1.21E+4nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Rattus norvegicus)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataKi:  1.58E+4nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Rattus norvegicus)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataKi:  3.10E+4nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in Oat1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataIC50:  7.40E+3nMAssay Description:TP_TRANSPORTER: inhibition of Adefovir uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataIC50:  1.23E+4nMAssay Description:TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataIC50:  6.30E+3nMAssay Description:TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataIC50:  1.25E+4nMAssay Description:TP_TRANSPORTER: inhibition of Urate uptake (Urate: 300 uM) in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of OAT1 (unknown origin)More data for this Ligand-Target Pair